Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours

Improved delivery materials are needed to enable siRNA transport across biological barriers, including the blood–brain barrier (BBB), to treat diseases like brain cancer. We engineered bioreducible nanoparticles for systemic siRNA delivery to patient-derived glioblastoma cells in an orthotopic mouse...

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Detaylı Bibliyografya
Yayımlandı:Nanoscale
Asıl Yazarlar: Karlsson, Johan, Rui, Yuan, Kozielski, Kristen L., Placone, Amanda L., Choi, Olivia, Tzeng, Stephany Y., Kim, Jayoung, Keyes, Jamal J., Bogorad, Max I., Gabrielson, Kathleen, Guerrero-Cazares, Hugo, Quiñones-Hinojosa, Alfredo, Searson, Peter C., Green, Jordan J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924015/
https://ncbi.nlm.nih.gov/pubmed/31612183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9nr04795f
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