Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

In chemotherapy-treated breast cancer, wild-type p53 preferentially induces senescence over apoptosis, resulting in a persisting cell population constituting residual disease that drives relapse and poor patient survival via the senescence-associated secretory phenotype. Understanding the properties...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Tonnessen-Murray, Crystal A., Frey, Wesley D., Rao, Sonia G., Shahbandi, Ashkan, Ungerleider, Nathan A., Olayiwola, Joy O., Murray, Lucas B., Vinson, Benjamin T., Chrisey, Douglas B., Lord, Christopher J., Jackson, James G.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829672/
https://ncbi.nlm.nih.gov/pubmed/31530580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904051
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