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Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

In chemotherapy-treated breast cancer, wild-type p53 preferentially induces senescence over apoptosis, resulting in a persisting cell population constituting residual disease that drives relapse and poor patient survival via the senescence-associated secretory phenotype. Understanding the properties...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Tonnessen-Murray, Crystal A., Frey, Wesley D., Rao, Sonia G., Shahbandi, Ashkan, Ungerleider, Nathan A., Olayiwola, Joy O., Murray, Lucas B., Vinson, Benjamin T., Chrisey, Douglas B., Lord, Christopher J., Jackson, James G.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829672/
https://ncbi.nlm.nih.gov/pubmed/31530580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904051
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