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Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival
In chemotherapy-treated breast cancer, wild-type p53 preferentially induces senescence over apoptosis, resulting in a persisting cell population constituting residual disease that drives relapse and poor patient survival via the senescence-associated secretory phenotype. Understanding the properties...
Guardat en:
| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Rockefeller University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829672/ https://ncbi.nlm.nih.gov/pubmed/31530580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904051 |
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