Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

In chemotherapy-treated breast cancer, wild-type p53 preferentially induces senescence over apoptosis, resulting in a persisting cell population constituting residual disease that drives relapse and poor patient survival via the senescence-associated secretory phenotype. Understanding the properties...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Tonnessen-Murray, Crystal A., Frey, Wesley D., Rao, Sonia G., Shahbandi, Ashkan, Ungerleider, Nathan A., Olayiwola, Joy O., Murray, Lucas B., Vinson, Benjamin T., Chrisey, Douglas B., Lord, Christopher J., Jackson, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829672/
https://ncbi.nlm.nih.gov/pubmed/31530580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904051
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