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Engulfment and cannibalism drive persistence of chemotherapy-treated tumor cells: can they be targeted?

The breast tumors that are most difficult to eradicate with chemotherapy have wild-type TP53 and preferentially enter senescence after treatment. One factor contributing to the persistence of senescent cells in residual disease: acquisition of a novel phenotype that allows cannibalism of entire cell...

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Pubblicato in:Mol Cell Oncol
Autori principali: Tonnessen-Murray, Crystal A., Jackson, James G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961664/
https://ncbi.nlm.nih.gov/pubmed/31993500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1688601
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