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The Regulation of Cellular Functions by the p53 Protein: Cellular Senescence

Transformed cells have properties that allow them to survive and proliferate inappropriately. These characteristics often arise as a result of mutations caused by DNA damage. p53 suppresses transformation by removing the proliferative or survival capacity of cells with DNA damage or inappropriate ce...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Tonnessen-Murray, Crystal A., Lozano, Guillermina, Jackson, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287062/
https://ncbi.nlm.nih.gov/pubmed/27881444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026112
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