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Senescence Regulation by the p53 Protein Family

p53, a guardian of the genome, exerts its tumor suppression activity by regulating a large number of downstream targets involved in cell cycle arrest, DNA repair, apoptosis, and cellular senescence. Although p53-mediated apoptosis is able to kill cancer cells, a role for cellular senescence in p53-d...

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Detalhes bibliográficos
Main Authors: Qian, Yingjuan, Chen, Xinbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784259/
https://ncbi.nlm.nih.gov/pubmed/23296650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-239-1_3
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