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The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress
P53 regulates an array of target genes, which mediates p53 tumor suppression by inducing cell cycle arrest, apoptosis, and cell survival. G protein-coupled receptors (GPCRs) belong to a superfamily of cell-surface molecules and are known to regulate cell proliferation, migration and survival. Here,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719689/ https://ncbi.nlm.nih.gov/pubmed/19602589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0621 |
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