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DEC1, a Basic Helix-Loop-Helix Transcription Factor and a Novel Target Gene of the p53 Family, Mediates p53-dependent Premature Senescence

Cellular senescence plays an important role in tumor suppression. p53 tumor suppressor has been reported to be crucial in cellular senescence. However, the underlying mechanism is poorly understood. In this regard, a cDNA microarray assay was performed to identify p53 targets involved in senescence....

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Autori principali: Qian, Yingjuan, Zhang, Jin, Yan, Bingfang, Chen, Xinbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118587/
https://ncbi.nlm.nih.gov/pubmed/18025081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708624200
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