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BH3 mimetics selectively eliminate chemotherapy-induced senescent cells and improve response in TP53 wild-type breast cancer
TP53 wild-type breast tumors rarely undergo a complete pathological response after chemotherapy treatment. These patients have an extremely poor survival rate and studies show these tumors preferentially undergo senescence instead of apoptosis. These senescent cells persist after chemotherapy and se...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Death Differ |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7560696/ https://ncbi.nlm.nih.gov/pubmed/32457483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0564-6 |
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