Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

In chemotherapy-treated breast cancer, wild-type p53 preferentially induces senescence over apoptosis, resulting in a persisting cell population constituting residual disease that drives relapse and poor patient survival via the senescence-associated secretory phenotype. Understanding the properties...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Tonnessen-Murray, Crystal A., Frey, Wesley D., Rao, Sonia G., Shahbandi, Ashkan, Ungerleider, Nathan A., Olayiwola, Joy O., Murray, Lucas B., Vinson, Benjamin T., Chrisey, Douglas B., Lord, Christopher J., Jackson, James G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829672/
https://ncbi.nlm.nih.gov/pubmed/31530580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201904051
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