Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure

Hypertension is a primary risk factor for cardiovascular diseases including myocardial infarction and stroke. Major determinants of blood pressure are vasodilatory factors such as nitric oxide (NO) released from the endothelium under the influence of fluid shear stress exerted by the flowing blood....

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Vydáno v:J Clin Invest
Hlavní autoři: Iring, Andras, Jin, Young-June, Albarrán-Juárez, Julián, Siragusa, Mauro, Wang, ShengPeng, Dancs, Péter T., Nakayama, Akiko, Tonack, Sarah, Chen, Min, Künne, Carsten, Sokol, Anna M., Günther, Stefan, Martínez, Alfredo, Fleming, Ingrid, Wettschureck, Nina, Graumann, Johannes, Weinstein, Lee S., Offermanns, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597232/
https://ncbi.nlm.nih.gov/pubmed/31205027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123825
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