Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure

Hypertension is a primary risk factor for cardiovascular diseases including myocardial infarction and stroke. Major determinants of blood pressure are vasodilatory factors such as nitric oxide (NO) released from the endothelium under the influence of fluid shear stress exerted by the flowing blood....

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Iring, Andras, Jin, Young-June, Albarrán-Juárez, Julián, Siragusa, Mauro, Wang, ShengPeng, Dancs, Péter T., Nakayama, Akiko, Tonack, Sarah, Chen, Min, Künne, Carsten, Sokol, Anna M., Günther, Stefan, Martínez, Alfredo, Fleming, Ingrid, Wettschureck, Nina, Graumann, Johannes, Weinstein, Lee S., Offermanns, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597232/
https://ncbi.nlm.nih.gov/pubmed/31205027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123825
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