Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure

Hypertension is a primary risk factor for cardiovascular diseases including myocardial infarction and stroke. Major determinants of blood pressure are vasodilatory factors such as nitric oxide (NO) released from the endothelium under the influence of fluid shear stress exerted by the flowing blood....

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Gepubliceerd in:J Clin Invest
Hoofdauteurs: Iring, Andras, Jin, Young-June, Albarrán-Juárez, Julián, Siragusa, Mauro, Wang, ShengPeng, Dancs, Péter T., Nakayama, Akiko, Tonack, Sarah, Chen, Min, Künne, Carsten, Sokol, Anna M., Günther, Stefan, Martínez, Alfredo, Fleming, Ingrid, Wettschureck, Nina, Graumann, Johannes, Weinstein, Lee S., Offermanns, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597232/
https://ncbi.nlm.nih.gov/pubmed/31205027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123825
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