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P2Y(2) and G(q)/G(11) control blood pressure by mediating endothelial mechanotransduction

Elevated blood pressure is a key risk factor for developing cardiovascular diseases. Blood pressure is largely determined by vasodilatory mediators, such as nitric oxide (NO), that are released from the endothelium in response to fluid shear stress exerted by the flowing blood. Previous work has ide...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Wang, ShengPeng, Iring, András, Strilic, Boris, Albarrán Juárez, Julián, Kaur, Harmandeep, Troidl, Kerstin, Tonack, Sarah, Burbiel, Joachim C., Müller, Christa E., Fleming, Ingrid, Lundberg, Jon O., Wettschureck, Nina, Offermanns, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563756/
https://ncbi.nlm.nih.gov/pubmed/26168216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81067
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