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P2Y(2) and G(q)/G(11) control blood pressure by mediating endothelial mechanotransduction
Elevated blood pressure is a key risk factor for developing cardiovascular diseases. Blood pressure is largely determined by vasodilatory mediators, such as nitric oxide (NO), that are released from the endothelium in response to fluid shear stress exerted by the flowing blood. Previous work has ide...
Gespeichert in:
| Veröffentlicht in: | J Clin Invest |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563756/ https://ncbi.nlm.nih.gov/pubmed/26168216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81067 |
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