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P2Y(2) and G(q)/G(11) control blood pressure by mediating endothelial mechanotransduction

Elevated blood pressure is a key risk factor for developing cardiovascular diseases. Blood pressure is largely determined by vasodilatory mediators, such as nitric oxide (NO), that are released from the endothelium in response to fluid shear stress exerted by the flowing blood. Previous work has ide...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Wang, ShengPeng, Iring, András, Strilic, Boris, Albarrán Juárez, Julián, Kaur, Harmandeep, Troidl, Kerstin, Tonack, Sarah, Burbiel, Joachim C., Müller, Christa E., Fleming, Ingrid, Lundberg, Jon O., Wettschureck, Nina, Offermanns, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563756/
https://ncbi.nlm.nih.gov/pubmed/26168216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81067
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