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Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are released from the endothelium under the influence of fluid shear stress exerted by flowing blood. Flow-induced endothelial release of ATP and subsequent activation of G(q)/G(11)–coupled purinergic P2Y(2)...

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Publicado en:J Clin Invest
Autores principales: Wang, ShengPeng, Chennupati, Ramesh, Kaur, Harmandeep, Iring, Andras, Wettschureck, Nina, Offermanns, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127677/
https://ncbi.nlm.nih.gov/pubmed/27797339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87343
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