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Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

Arterial blood pressure is controlled by vasodilatory factors such as nitric oxide (NO) that are released from the endothelium under the influence of fluid shear stress exerted by flowing blood. Flow-induced endothelial release of ATP and subsequent activation of G(q)/G(11)–coupled purinergic P2Y(2)...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Wang, ShengPeng, Chennupati, Ramesh, Kaur, Harmandeep, Iring, Andras, Wettschureck, Nina, Offermanns, Stefan
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127677/
https://ncbi.nlm.nih.gov/pubmed/27797339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87343
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