Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation

The vascular endothelium is constantly exposed to mechanical forces, including fluid shear stress exerted by the flowing blood. Endothelial cells can sense different flow patterns and convert the mechanical signal of laminar flow into atheroprotective signals, including eNOS activation, whereas dist...

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Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Albarrán-Juárez, Julián, Iring, Andras, Wang, ShengPeng, Joseph, Sayali, Grimm, Myriam, Strilic, Boris, Wettschureck, Nina, Althoff, Till F., Offermanns, Stefan
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170174/
https://ncbi.nlm.nih.gov/pubmed/30194266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180483
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