Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation

The vascular endothelium is constantly exposed to mechanical forces, including fluid shear stress exerted by the flowing blood. Endothelial cells can sense different flow patterns and convert the mechanical signal of laminar flow into atheroprotective signals, including eNOS activation, whereas dist...

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Vydáno v:J Exp Med
Hlavní autoři: Albarrán-Juárez, Julián, Iring, Andras, Wang, ShengPeng, Joseph, Sayali, Grimm, Myriam, Strilic, Boris, Wettschureck, Nina, Althoff, Till F., Offermanns, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170174/
https://ncbi.nlm.nih.gov/pubmed/30194266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180483
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