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Procontractile G protein–mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling

Vascular smooth muscle (Sm) cells (VSMCs) are highly plastic. Their differentiation state can be regulated by serum response factor (SRF), which activates genes involved in Sm differentiation and proliferation by recruiting cofactors, such as members of the myocardin family and ternary complex facto...

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Detalhes bibliográficos
Main Authors: Althoff, Till F., Juárez, Julián Albarrán, Troidl, Kerstin, Tang, Cong, Wang, Shengpeng, Wirth, Angela, Takefuji, Mikito, Wettschureck, Nina, Offermanns, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501360/
https://ncbi.nlm.nih.gov/pubmed/23129751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120350
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