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Disturbed flow–induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis

Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the expression of leukocyte adhesion molecules and ch...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Nakayama, Akiko, Albarrán-Juárez, Julián, Liang, Guozheng, Roquid, Kenneth Anthony, Iring, András, Tonack, Sarah, Chen, Min, Müller, Oliver J., Weinstein, Lee S., Offermanns, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714404/
https://ncbi.nlm.nih.gov/pubmed/33268595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140485
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