Disturbed flow–induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis

Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the expression of leukocyte adhesion molecules and ch...

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Publicat a:JCI Insight
Autors principals: Nakayama, Akiko, Albarrán-Juárez, Julián, Liang, Guozheng, Roquid, Kenneth Anthony, Iring, András, Tonack, Sarah, Chen, Min, Müller, Oliver J., Weinstein, Lee S., Offermanns, Stefan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714404/
https://ncbi.nlm.nih.gov/pubmed/33268595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140485
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