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Disturbed flow–induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis

Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the expression of leukocyte adhesion molecules and ch...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Nakayama, Akiko, Albarrán-Juárez, Julián, Liang, Guozheng, Roquid, Kenneth Anthony, Iring, András, Tonack, Sarah, Chen, Min, Müller, Oliver J., Weinstein, Lee S., Offermanns, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714404/
https://ncbi.nlm.nih.gov/pubmed/33268595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140485
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