Disturbed flow–induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis

Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the expression of leukocyte adhesion molecules and ch...

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Опубликовано в: :JCI Insight
Главные авторы: Nakayama, Akiko, Albarrán-Juárez, Julián, Liang, Guozheng, Roquid, Kenneth Anthony, Iring, András, Tonack, Sarah, Chen, Min, Müller, Oliver J., Weinstein, Lee S., Offermanns, Stefan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714404/
https://ncbi.nlm.nih.gov/pubmed/33268595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140485
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