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Disturbed flow–induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis

Atherosclerosis develops preferentially in areas of the arterial system, in which blood flow is disturbed. Exposure of endothelial cells to disturbed flow has been shown to induce inflammatory signaling, including NF-κB activation, which leads to the expression of leukocyte adhesion molecules and ch...

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Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Nakayama, Akiko, Albarrán-Juárez, Julián, Liang, Guozheng, Roquid, Kenneth Anthony, Iring, András, Tonack, Sarah, Chen, Min, Müller, Oliver J., Weinstein, Lee S., Offermanns, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7714404/
https://ncbi.nlm.nih.gov/pubmed/33268595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140485
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