A model for the impact of FFPE section thickness on gene copy number measurement by FISH

Fluorescent in situ hybridization (FISH) assays to detect gene amplification such as HER2 or MET in tumors are used for prognosis evaluation and selection of targeted therapies. Although FISH guidelines recommended 4~6 μm FFPE sections, many laboratories use 2~3 μm sections, which is a common practi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yu, Jiyan, Wang, Qi, Xue, Pu, Zheng, Li, Mo, Juanfen, Chen, Liangye, Yin, Manxiang, Huang, Yueyan, Bao, Yi, Ding, Feng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525178/
https://ncbi.nlm.nih.gov/pubmed/31101839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44015-7
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