FrenchFISH: Poisson Models for Quantifying DNA Copy Number From Fluorescence In Situ Hybridization of Tissue Sections

Chromosomal aberration and DNA copy number change are robust hallmarks of cancer. The gold standard for detecting copy number changes in tumor cells is fluorescence in situ hybridization (FISH) using locus-specific probes that are imaged as fluorescent spots. However, spot counting often does not pe...

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Detalhes bibliográficos
Publicado no:JCO Clin Cancer Inform
Main Authors: Macintyre, Geoff, Piskorz, Anna M., Berman, Adam, Ross, Edith, Morse, David B., Yuan, Ke, Ennis, Darren, Pike, Jeremy A., Goranova, Teodora, McNeish, Iain A., Brenton, James D., Markowetz, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2021
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140799/
https://ncbi.nlm.nih.gov/pubmed/33570999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.20.00075
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