FrenchFISH: Poisson Models for Quantifying DNA Copy Number From Fluorescence In Situ Hybridization of Tissue Sections

Chromosomal aberration and DNA copy number change are robust hallmarks of cancer. The gold standard for detecting copy number changes in tumor cells is fluorescence in situ hybridization (FISH) using locus-specific probes that are imaged as fluorescent spots. However, spot counting often does not pe...

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Veröffentlicht in:JCO Clin Cancer Inform
Hauptverfasser: Macintyre, Geoff, Piskorz, Anna M., Berman, Adam, Ross, Edith, Morse, David B., Yuan, Ke, Ennis, Darren, Pike, Jeremy A., Goranova, Teodora, McNeish, Iain A., Brenton, James D., Markowetz, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2021
Schlagworte:
Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8140799/
https://ncbi.nlm.nih.gov/pubmed/33570999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.20.00075
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