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Allele-specific multi-sample copy number segmentation in ASCAT

MOTIVATION: Allele-specific copy number alterations are commonly used to trace the evolution of tumours. A key step of the analysis is to segment genomic data into regions of constant copy number. For precise phylogenetic inference, breakpoints shared between samples need to be aligned to each other...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Ross, Edith M., Haase, Kerstin, Van Loo, Peter, Markowetz, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317109/
https://ncbi.nlm.nih.gov/pubmed/32449758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa538
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