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Allele-specific multi-sample copy number segmentation in ASCAT

MOTIVATION: Allele-specific copy number alterations are commonly used to trace the evolution of tumours. A key step of the analysis is to segment genomic data into regions of constant copy number. For precise phylogenetic inference, breakpoints shared between samples need to be aligned to each other...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Ross, Edith M., Haase, Kerstin, Van Loo, Peter, Markowetz, Florian
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317109/
https://ncbi.nlm.nih.gov/pubmed/32449758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa538
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