Allele-specific copy number analysis of tumors

We present an allele-specific copy number analysis of the in vivo breast cancer genome. We describe a unique bioinformatics approach, ASCAT (allele-specific copy number analysis of tumors), to accurately dissect the allele-specific copy number of solid tumors, simultaneously estimating and adjusting...

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Détails bibliographiques
Auteurs principaux: Van Loo, Peter, Nordgard, Silje H., Lingjærde, Ole Christian, Russnes, Hege G., Rye, Inga H., Sun, Wei, Weigman, Victor J., Marynen, Peter, Zetterberg, Anders, Naume, Bjørn, Perou, Charles M., Børresen-Dale, Anne-Lise, Kristensen, Vessela N.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947907/
https://ncbi.nlm.nih.gov/pubmed/20837533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009843107
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