Integrated study of copy number states and genotype calls using high-density SNP arrays

We propose a statistical framework, named genoCN, to simultaneously dissect copy number states and genotypes using high-density SNP (single nucleotide polymorphism) arrays. There are at least two types of genomic DNA copy number differences: copy number variations (CNVs) and copy number aberrations...

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Detalhes bibliográficos
Main Authors: Sun, Wei, Wright, Fred A., Tang, Zhengzheng, Nordgard, Silje H., Loo, Peter Van, Yu, Tianwei, Kristensen, Vessela N., Perou, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935461/
https://ncbi.nlm.nih.gov/pubmed/19581427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp493
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