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Bivariate segmentation of SNP-array data for allele-specific copy number analysis in tumour samples
BACKGROUND: SNP arrays output two signals that reflect the total genomic copy number (LRR) and the allelic ratio (BAF), which in combination allow the characterisation of allele-specific copy numbers (ASCNs). While methods based on hidden Markov models (HMMs) have been extended from array comparativ...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599505/ https://ncbi.nlm.nih.gov/pubmed/23497144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-84 |
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