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Bivariate segmentation of SNP-array data for allele-specific copy number analysis in tumour samples
BACKGROUND: SNP arrays output two signals that reflect the total genomic copy number (LRR) and the allelic ratio (BAF), which in combination allow the characterisation of allele-specific copy numbers (ASCNs). While methods based on hidden Markov models (HMMs) have been extended from array comparativ...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599505/ https://ncbi.nlm.nih.gov/pubmed/23497144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-84 |
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