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Precise inference of copy number alterations in tumor samples from SNP arrays

Motivation: The accurate detection of copy number alterations (CNAs) in human genomes is important for understanding susceptibility to cancer and mechanisms of tumor progression. CNA detection in tumors from single nucleotide polymorphism (SNP) genotyping arrays is a challenging problem due to pheno...

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Bibliografische gegevens
Hoofdauteurs: Chen, Gary K., Chang, Xiao, Curtis, Christina, Wang, Kai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834792/
https://ncbi.nlm.nih.gov/pubmed/24021380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt521
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