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Precise inference of copy number alterations in tumor samples from SNP arrays

Motivation: The accurate detection of copy number alterations (CNAs) in human genomes is important for understanding susceptibility to cancer and mechanisms of tumor progression. CNA detection in tumors from single nucleotide polymorphism (SNP) genotyping arrays is a challenging problem due to pheno...

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Hlavní autoři: Chen, Gary K., Chang, Xiao, Curtis, Christina, Wang, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834792/
https://ncbi.nlm.nih.gov/pubmed/24021380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt521
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