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Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping data

BACKGROUND: The detection of genomic copy number alterations (CNA) in cancer based on SNP arrays requires methods that take into account tumour specific factors such as normal cell contamination and tumour heterogeneity. A number of tools have been recently developed but their performance needs yet...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mosén-Ansorena, David, Aransay, Ana María, Rodríguez-Ezpeleta, Naiara
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472297/
https://ncbi.nlm.nih.gov/pubmed/22870940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-192
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