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VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity

VCF2CNA is a tool (Linux commandline or web-interface) for copy-number alteration (CNA) analysis and tumor purity estimation of paired tumor-normal VCF variant file formats. It operates on whole genome and whole exome datasets. To benchmark its performance, we applied it to 46 adult glioblastoma and...

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Sonraí Bibleagrafaíochta
Foilsithe in:Sci Rep
Main Authors: Putnam, Daniel K., Ma, Xiaotu, Rice, Stephen V., Liu, Yu, Newman, Scott, Zhang, Jinghui, Chen, Xiang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637131/
https://ncbi.nlm.nih.gov/pubmed/31316100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45938-x
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