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ACNE: a summarization method to estimate allele-specific copy numbers for Affymetrix SNP arrays

Motivation: Current algorithms for estimating DNA copy numbers (CNs) borrow concepts from gene expression analysis methods. However, single nucleotide polymorphism (SNP) arrays have special characteristics that, if taken into account, can improve the overall performance. For example, cross hybridiza...

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Main Authors: Ortiz-Estevez, Maria, Bengtsson, Henrik, Rubio, Angel
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913655/
https://ncbi.nlm.nih.gov/pubmed/20529889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq300
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