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ACNE: a summarization method to estimate allele-specific copy numbers for Affymetrix SNP arrays

Motivation: Current algorithms for estimating DNA copy numbers (CNs) borrow concepts from gene expression analysis methods. However, single nucleotide polymorphism (SNP) arrays have special characteristics that, if taken into account, can improve the overall performance. For example, cross hybridiza...

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Bibliografiske detaljer
Main Authors: Ortiz-Estevez, Maria, Bengtsson, Henrik, Rubio, Angel
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913655/
https://ncbi.nlm.nih.gov/pubmed/20529889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq300
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