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Neoantigens in ovarian cancer: embarrassment of riches or needles in a haystack?

Comprehensive genomic and transcriptomic analysis demonstrates that tumor-infiltrating T lymphocytes that react to mutated neo-epitopes could be identified in recurrent ovarian cancer. Two of these T cell populations reacted against TP53 hotspot missense mutations that are present in a wide variety...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Autor principal: McNeish, Iain A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6215482/
https://ncbi.nlm.nih.gov/pubmed/29980529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1731
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