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The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma

PURPOSE: Ovarian high-grade serous carcinoma (HGSC) is usually diagnosed at late stage. We investigated whether late-stage HGSC has unique genomic characteristics consistent with acquisition of evolutionary advantage compared with early-stage tumors. EXPERIMENTAL DESIGN: We performed targeted next-g...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Cheng, Zhao, Mirza, Hasan, Ennis, Darren P., Smith, Philip, Morrill Gavarró, Lena, Sokota, Chishimba, Giannone, Gaia, Goranova, Theodora, Bradley, Thomas, Piskorz, Anna, Lockley, Michelle, Kaur, Baljeet, Singh, Naveena, Tookman, Laura A., Krell, Jonathan, McDermott, Jacqueline, Macintyre, Geoffrey, Markowetz, Florian, Brenton, James D., McNeish, Iain A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612959/
https://ncbi.nlm.nih.gov/pubmed/35398881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-21-1643
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