The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma

PURPOSE: Ovarian high-grade serous carcinoma (HGSC) is usually diagnosed at late stage. We investigated whether late-stage HGSC has unique genomic characteristics consistent with acquisition of evolutionary advantage compared with early-stage tumors. EXPERIMENTAL DESIGN: We performed targeted next-g...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Cheng, Zhao, Mirza, Hasan, Ennis, Darren P., Smith, Philip, Morrill Gavarró, Lena, Sokota, Chishimba, Giannone, Gaia, Goranova, Theodora, Bradley, Thomas, Piskorz, Anna, Lockley, Michelle, Kaur, Baljeet, Singh, Naveena, Tookman, Laura A., Krell, Jonathan, McDermott, Jacqueline, Macintyre, Geoffrey, Markowetz, Florian, Brenton, James D., McNeish, Iain A.
Format: Artigo
Jezik:Inglês
Izdano: American Association for Cancer Research 2022
Teme:
Translational Cancer Mechanisms and Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612959/
https://ncbi.nlm.nih.gov/pubmed/35398881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-21-1643
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