High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

BACKGROUND: A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high failure rates compared to fresh frozen samp...

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Detalhes bibliográficos
Main Authors: Wang, Yuker, Carlton, Victoria EH, Karlin-Neumann, George, Sapolsky, Ronald, Zhang, Li, Moorhead, Martin, Wang, Zhigang C, Richardson, Andrea L, Warren, Robert, Walther, Axel, Bondy, Melissa, Sahin, Aysegul, Krahe, Ralf, Tuna, Musaffe, Thompson, Patricia A, Spellman, Paul T, Gray, Joe W, Mills, Gordon B, Faham, Malek
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649948/
https://ncbi.nlm.nih.gov/pubmed/19228381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-8
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