High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

BACKGROUND: A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high failure rates compared to fresh frozen samp...

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Main Authors: Wang, Yuker, Carlton, Victoria EH, Karlin-Neumann, George, Sapolsky, Ronald, Zhang, Li, Moorhead, Martin, Wang, Zhigang C, Richardson, Andrea L, Warren, Robert, Walther, Axel, Bondy, Melissa, Sahin, Aysegul, Krahe, Ralf, Tuna, Musaffe, Thompson, Patricia A, Spellman, Paul T, Gray, Joe W, Mills, Gordon B, Faham, Malek
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Technical Advance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649948/
https://ncbi.nlm.nih.gov/pubmed/19228381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-8
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