High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

BACKGROUND: A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high failure rates compared to fresh frozen samp...

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Autori principali: Wang, Yuker, Carlton, Victoria EH, Karlin-Neumann, George, Sapolsky, Ronald, Zhang, Li, Moorhead, Martin, Wang, Zhigang C, Richardson, Andrea L, Warren, Robert, Walther, Axel, Bondy, Melissa, Sahin, Aysegul, Krahe, Ralf, Tuna, Musaffe, Thompson, Patricia A, Spellman, Paul T, Gray, Joe W, Mills, Gordon B, Faham, Malek
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649948/
https://ncbi.nlm.nih.gov/pubmed/19228381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-8
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