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Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers

BACKGROUND: Archived formalin-fixed, paraffin-embedded specimens represent an important resource for pharmacogenomic analysis in retrospective clinical studies but the quality of results from formalin-fixed, paraffin-embedded samples is of concern due to the fact of the degradation of DNAs and RNAs...

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Detalhes bibliográficos
Main Authors: Yu, Jinsheng, Miller, Ryan, Zhang, Wanghai, Sharma, Mala, Holtschlag, Vicky, Watson, Mark A, McLeod, Howard L
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575840/
https://ncbi.nlm.nih.gov/pubmed/18855534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.10.1459
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