Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples

Genomic technologies, such as array comparative genomic hybridization (aCGH), increasingly offer definitive gene dosage profiles in clinical samples. Historically, copy number profiling was limited to large fresh-frozen tumors where intact DNA could be readily extracted. Genomic analyses of pre-neop...

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Bibliografski detalji
Glavni autori: Hostetter, Galen, Kim, Su Young, Savage, Stephanie, Gooden, Gerald C., Barrett, Michael, Zhang, Jian, Alla, Lalitamba, Watanabe, April, Einspahr, Janine, Prasad, Anil, Nickoloff, Brian J., Carpten, John, Trent, Jeffrey, Alberts, David, Bittner, Michael
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Methods Online
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811007/
https://ncbi.nlm.nih.gov/pubmed/19875416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp881
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