Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples

Genomic technologies, such as array comparative genomic hybridization (aCGH), increasingly offer definitive gene dosage profiles in clinical samples. Historically, copy number profiling was limited to large fresh-frozen tumors where intact DNA could be readily extracted. Genomic analyses of pre-neop...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hostetter, Galen, Kim, Su Young, Savage, Stephanie, Gooden, Gerald C., Barrett, Michael, Zhang, Jian, Alla, Lalitamba, Watanabe, April, Einspahr, Janine, Prasad, Anil, Nickoloff, Brian J., Carpten, John, Trent, Jeffrey, Alberts, David, Bittner, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
Methods Online
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811007/
https://ncbi.nlm.nih.gov/pubmed/19875416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp881
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