Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples

Genomic technologies, such as array comparative genomic hybridization (aCGH), increasingly offer definitive gene dosage profiles in clinical samples. Historically, copy number profiling was limited to large fresh-frozen tumors where intact DNA could be readily extracted. Genomic analyses of pre-neop...

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Detalles Bibliográficos
Autores principales: Hostetter, Galen, Kim, Su Young, Savage, Stephanie, Gooden, Gerald C., Barrett, Michael, Zhang, Jian, Alla, Lalitamba, Watanabe, April, Einspahr, Janine, Prasad, Anil, Nickoloff, Brian J., Carpten, John, Trent, Jeffrey, Alberts, David, Bittner, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
Materias:
Methods Online
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811007/
https://ncbi.nlm.nih.gov/pubmed/19875416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp881
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