Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment

The opioid crisis is a significant public health issue with more than 115 people dying from opioid overdose per day in the United States. The aim of the present study was to characterize the in vitro and in vivo pharmacological effects of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Obeng, Samuel, Jali, Abdulmajeed, Zheng, Yi, Wang, Huiqun, Schwienteck, Kathryn L., Chen, Chongguang, Stevens, David L., Akbarali, Hamid I., Dewey, William L., Banks, Mathew L., Liu-Chen, Lee-Yuan, Selley, Dana E., Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520168/
https://ncbi.nlm.nih.gov/pubmed/30758946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00038
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