Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment

The opioid crisis is a significant public health issue with more than 115 people dying from opioid overdose per day in the United States. The aim of the present study was to characterize the in vitro and in vivo pharmacological effects of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-...

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發表在:ACS Chem Neurosci
Main Authors: Obeng, Samuel, Jali, Abdulmajeed, Zheng, Yi, Wang, Huiqun, Schwienteck, Kathryn L., Chen, Chongguang, Stevens, David L., Akbarali, Hamid I., Dewey, William L., Banks, Mathew L., Liu-Chen, Lee-Yuan, Selley, Dana E., Zhang, Yan
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520168/
https://ncbi.nlm.nih.gov/pubmed/30758946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00038
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