Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment

The opioid crisis is a significant public health issue with more than 115 people dying from opioid overdose per day in the United States. The aim of the present study was to characterize the in vitro and in vivo pharmacological effects of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Chem Neurosci
Main Authors: Obeng, Samuel, Jali, Abdulmajeed, Zheng, Yi, Wang, Huiqun, Schwienteck, Kathryn L., Chen, Chongguang, Stevens, David L., Akbarali, Hamid I., Dewey, William L., Banks, Mathew L., Liu-Chen, Lee-Yuan, Selley, Dana E., Zhang, Yan
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520168/
https://ncbi.nlm.nih.gov/pubmed/30758946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00038
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