D(2) Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine

Functionally selective G protein-coupled receptor ligands are valuable tools for deciphering the roles of downstream signaling pathways that potentially contribute to therapeutic effects versus side effects. Recently, we discovered both G(i/o)-biased and β-arrestin2-biased D(2) receptor agonists bas...

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Detaylı Bibliyografya
Yayımlandı:J Med Chem
Asıl Yazarlar: Shen, Yudao, McCorvy, John D., Martini, Michael L., Rodriguiz, Ramona M., Pogorelov, Vladimir M., Ward, Karen M., Wetsel, William C., Liu, Jing, Roth, Bryan L., Jin, Jian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509010/
https://ncbi.nlm.nih.gov/pubmed/30964661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b00508
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