5-HT(2C) Agonists Modulate Schizophrenia-Like Behaviors in Mice

All FDA-approved antipsychotic drugs (APDs) target primarily dopamine D(2) or serotonin (5-HT(2A)) receptors, or both; however, these medications are not universally effective, they may produce undesirable side effects, and provide only partial amelioration of negative and cognitive symptoms. The he...

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Publicado en:Neuropsychopharmacology
Autores principales: Pogorelov, Vladimir M, Rodriguiz, Ramona M, Cheng, Jianjun, Huang, Mei, Schmerberg, Claire M, Meltzer, Herbert Y, Roth, Bryan L, Kozikowski, Alan P, Wetsel, William C
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603814/
https://ncbi.nlm.nih.gov/pubmed/28294132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.52
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